Key References List
References for artificial sweeteners and cancer risk
Debras C, Chazelas E, Srour B, et al. Artificial sweeteners and cancer risk: Results from the NutriNet-Santé population-based cohort study. PLoS Med. 2022;19(3):e1003950.
Landrigan PJ, Straif K. Aspartame and cancer – new evidence for causation. Environ Health. 2021;20(1):42.
Lohner S, Toews I, Meerpohl JJ. Health outcomes of non-nutritive sweeteners: analysis of the research landscape. Nutr J. 2017;16(1):55.
Choudhary AK, Pretorius E. Revisiting the safety of aspartame [published correction appears in Nutr Rev. 2018 Apr 1;76(4):301] [published correction appears in Nutr Rev. 2018 Nov 1;76(11):860]. Nutr Rev. 2017;75(9):718-730.
Raoul P, Cintoni M, Palombaro M, et al. Food Additives, a Key Environmental Factor in the Development of IBD through Gut Dysbiosis. Microorganisms. 2022;10(1):167.
Malik VS, Hu FB. The role of sugar-sweetened beverages in the global epidemics of obesity and chronic diseases. Nat Rev Endocrinol. 2022;18(4):205-218.
References for Obesity and Damage
Burke GL, Bertoni AG, Shea S, Tracy R, Watson KE, Blumenthal RS et al. The impact of obesity on cardiovascular disease risk factors and subclinical vascular disease: the Multi-Ethnic Study of Atherosclerosis. Arch Intern Med 2008; 168:928-935.
Yiannikouris F, Karounos M, Charnigo R, English VL, Rateri DL, Daugherty A, Cassis LA. Adipocyte-specific deficiency of angiotensinogen decreases plasma angiotensinogen concentration and systolic blood pressure in mice. Am J Physiol Regul Integr Comp Physiol. 2012; 302:R244-51.
Hui Xie, John A. Bevan. Ox-LDL enhances myogenic tone in the rabbit posterior cerebral artery through the release of endothelin-1. Stroke. 30:2423-2430; 1999.
Pierce GL, Beske SD, Lawson BR, Southall KL, Benay FJ, Donato AJ et al. Weight loss alone improves conduit and resistance artery endothelial function in young and older overweight/obese adults. Hypertension 2008; 52:72-79.
Possible involvement of the adipose tissue renin-angiotensin system in the pathophysiology of obesity and obesity-related disorders. Obes Rev 2003; 4:43-55.
Turnbaugh PJ, Ley RE, Mahowald MA, Magrini V, Mardis ER, Gordon JI. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature. 2006; 444:1027–1031.
Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan A, Ley RE. A core gut microbiome in obese and lean twins. Nature. 2009; 457:480–484.
Buford TW. (Dis)Trust your gut: the gut microbiome in age-related inflammation, health, and disease. (Review) Microbiome 2017; 5:80
Nagpal R, Mainali R, Ahmadi S, Wang S, Singh R, Kavanagh K, Kitzman DW, Kushugulova A, Marotta F, Yadav H. Gut microbiome and aging: Physiological and mechanistic insights. Nutr Healthy Aging 2018; 4:267-285.
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References for Anticancer Effects of Melatonin
Reiter RJ, Rosales-Corral SA, Tan DX, Acuna-Castroviejo D, Qin L, Yang SF, Xu K. Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis. Int J Mol Sci. 2017; 18(4). pii: E843.
Liu J, Clough SJ, Hutchinson AJ, Adamah-Biassi EB, Popovska-Gorevski M, Dubocovich ML. MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective. Annu Rev Pharmacol Toxicol. 2016; 56:361-83.
Reiter RJ, Mayo JC, Tan DX, Sainz RM, Alatorre-Jimenez M, Qin L. Melatonin as an antioxidant: under promises but over delivers. J Pineal Res. 2016t; 61:253-78.
Karaaslan C, Suzen S. Antioxidant properties of melatonin and its potential action in diseases. Curr Top Med Chem. 2015; 15:894-903.
Li Y, Li S, Zhou Y, Meng X, Zhang JJ, Xu DP, Li HB. Melatonin for the prevention and treatment of cancer. Oncotarget. 2017; 8:39896-39921.
Pohanka M. Impact of melatonin on immunity: a review. Central European J Med. 2013; 8:369–376.
Bondy SC, Campbell A. Mechanisms Underlying Tumor Suppressive Properties of Melatonin. Int J Mol Sci. 2018;1 9(8). pii: E2205.
Goradel NH, Asghari MH, Moloudizargari M, Negahdari B, Haghi-Aminjan H, Abdollahi M. Melatonin as an angiogenesis inhibitor to combat cancer: Mechanistic evidence. Toxicol Appl Pharmacol. 2017; 335:56-63.
Carrillo-Vico A, Lardone PJ, Alvarez-Sánchez N, Rodríguez-Rodríguez A, Guerrero JM. Melatonin: buffering the immune system. Int J Mol Sci. 2013; 14:8638-83.
Gurer-Orhan H, Ince E, Konyar D, Saso L, Suzen S. The Role of Oxidative Stress Modulators in Breast Cancer. Curr Med Chem. 2018; 25:4084-4101.
Xin Z, Jiang S, Jiang P, Yan X, Fan C, Di S, Wu G, Yang Y, Reiter RJ, Ji G. Melatonin as a treatment for gastrointestinal cancer: a review. J Pineal Res. 2015; 58:375-87.
González-González A, Mediavilla MD, Sánchez-Barceló EJ. Melatonin: A Molecule for Reducing Breast Cancer Risk. Molecules. 2018; 23. pii: E336.
Jaworek J, Leja-Szpak A. Melatonin influences pancreatic cancerogenesis. Histol Histopathol. 2014; 29:423-31.
Ma Z, Yang Y, Fan C, Han J, Wang D, Di S, Hu W, Liu D, Li X, Reiter RJ, Yan X. Melatonin as a potential anticarcinogen for non-small-cell lung cancer. Oncotarget. 2016; 7:46768-46784.