Category Archives: Pancreatic Cancer

Why It Is Critical to Prevent Diabetes: Association with Pancreatic Cancer

By Hui Xie-Zukauskas

Stop diabetes logoHere are a couple of sobering statistics: A total of 25.8 million children and adults in the United States and 347 million worldwide have diabetes. These figures demonstrate clearly that diabetes has become a pandemic in today’s world.

Preventing diabetes in our own and our families’ lives should be of great concern to us for several reasons. One reason is that a diagnosis of diabetes can result in life-altering changes needed to manage the disease. But there is another big reason such a diagnosis is troubling, and today I’m going to focus on that reason. I’m going to talk about the urgent need for diabetes prevention because diabetes is a known risk factor of pancreatic cancer.

What is diabetes?

Diabetes is a chronic disease in which the body either cannot make enough insulin (Type 1) or cannot effectively uses its own insulin (Type 2). Insulin is a pancreatic hormone that regulates blood sugar by facilitating glucose (sugar) storage in the cells for energy. When insulin fails to do its job, blood sugar levels rise.

Type 2 diabetes affects 90% of people with diabetes around the world and results largely from being overweight and physical inactivity. High blood sugar levels can lead to long-term damage to cells and organs, as seen in complications like high blood pressure, blindness, kidney disease, and nerve disorders.

What is pancreatic cancer?

Pancreatic cancer is a deadly disease in which cancerous cells develop inside the pancreas, an organ that produces hormones such as insulin and digestive juices. (See more on “The Rule of Three for Pancreatic Cancer Prevention”).

What is the relationship between the two?

Accumulated studies have revealed a positive association between diabetes and pancreatic malignancy, although the details of what is the exact causal relationship are complex and controversial. Diabetes may be either a symptom or a risk factor of pancreatic cancer. Here are some facts showing why it has been concluded that the two maladies are connected:

-          Pancreatic cancer occurs two times more in people who have diabetes than in those without diabetes.

-          Approximately 80% of patients diagnosed with pancreatic cancer, when diabetes co-exists, often have a progressive malignancy.

-          Patients with new-onset Type 2 diabetes are at a higher risk of developing pancreatic cancer. When suffering from cancer, they have a worse rate of long-term survival and a higher rate of post-surgical complications.

-          45% of pancreatic cancer patients have diabetes and more than half of diabetes cases are newly developed. Thus diabetes has been proposed to be a clue for early cancer diagnosis.

In summary, diabetes is considered to be a risk factor of pancreatic cancer and has a negative impact on the prognosis and outcome of this deadly form of cancer. That is one excellent reason why it is so important to prevent diabetes.

To help in that prevention, here are a couple of small, easy, and effective dietary practices that can be achieved on a daily basis:

  • To help keep your blood glucose under control, avoid foods high in sugar. High sugar-containing foods include rich desserts, candies, ice cream, sweetened drinks and fruits packed in syrup. Furthermore, many processed foods hold excessive sugar.
  • Drink plenty of water, which benefits your body in many ways, especially helping remove metabolic by-products when hyperglycemia occurs.

Following these two suggestions daily can go a long way toward helping keep you free of the plague of diabetes… And oh yes, don’t forget to include an appropriate measure of exercise in your lifestyle!

Until my next cancer prevention blog, I wish you Good Health, Good Living and Happy Thanksgiving!


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The Rule of Three for Pancreatic Cancer Prevention

By Hui Xie-Zukauskas

Imagine this – it starts from deeper in the abdomen, inside the pancreas, an organ between the stomach and backbone, gradually hits a person at 60s with no sign or some digestive discomfort, pain in the abdomen, yellowish skin, and then unexplained weight loss. After that, it aggressively takes the person’s life. That is pancreatic cancer.

pancreas-cancer_Med.WorldPancreatic cancer is one of the deadliest forms of all cancer. With current medical technology, the five-year survival rate is only six percent. The cases are apparently increasing, as about 45,000 people are expected to be diagnosed with pancreatic cancer in 2013; among them 38,000 people will die of the disease this year.

To help raise awareness of this devastating disease among those who are unfamiliar with pancreatic cancer, let me use “The Rule of Three” to highlight pancreatic cancer prevention.

Rule #1: Never smoke, and live a healthy lifestyle.

Cigarette smoking is a well-established risk factor for pancreatic cancer. It’s also important to maintain a healthy lifestyle, eat more plant-based foods and less meat, stay physically active, and keep a healthy weight. Obesity has also been linked to pancreatic cancer.

Rule #2: Prevent and treat chronic pancreatitis.

Inflammation plays a role in developing pancreatic cancer, and chronic pancreatitis is a known risk factor. In addition, pancreatic cancer is more common among individuals with histories of cirrhosis (a chronic liver disease), diabetes, and previous surgery to the upper digestive tract. Pancreatic cancer may also be attributed to a pathogen for periodontal disease (named porphyromonas gingivalis).

Rule #3: Keep diabetes at the bay.

Type 2 diabetes is closely associated with pancreatic cancer, as a body of research reveals. As the population ages and the obesity epidemic continues, the incidence of diabetes is predicted to rise. People with diabetes are more likely to develop pancreatic cancer than those free of diabetes.

A final point

Still, as is true for other cancers, early detection is always important for combating the pancreatic cancer. This is particularly critical for those with a family history of this disease, because the risk can be doubled or tripled by familial pancreatic cancer.

In brief, pancreatic cancer is deadly, but you can lower your risk by not smoking, preventing pancreatitis and diabetes, and raising your awareness about the importance of living a healthy lifestyle.


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